Altis Biosystem’s gastrointestinal product family is called RepliGut. The RepliGut system is a unique, mammalian (human and animal) stem cell technology that recreates the intestinal epithelium in a continuous layer of stem and differentiated cells. This platform is used in preclinical studies for disease modeling, microbiome research, and compound screening. The primary users of our organ on a chip product would be pharmaceutical companies and CROs.
RepliGut was developed to replace Caco-2 cells (cancer cells) and animals, which are currently used as a part of compound screening during preclinical studies, before human testing. This stem cell technology should provide more predictive results than current methods, since it uses normal gastrointestinal tissue.
Our product comes in two formats: